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- W2356177554 abstract "GH binding to its receptor(GHR) initiates intracellular signal transduction and then affects the function of endocrine axis(GHRH-GH-IGF-1),and plays an important role in the development of the cartilage.At the same time,GHR genovariation is closely correlated with ISS.Allthough SNPs of GHR widely exists in common every one and patients with ISS,different SNP situs has different influence on the function of GHR,and SNP of GHR has close relationship with the genesis of partal patients with ISS.So,SNP of GHR maybe the important factor in affecting the level of IGF-1 and partial patients with ISS." @default.
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- W2356177554 date "2007-01-01" @default.
- W2356177554 modified "2023-09-24" @default.
- W2356177554 title "Correlation between Gene Polymorphisms of GHR and Idiopathic Short Stature" @default.
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