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- W2356179968 abstract "Objective: To observe the effect of hyperbaric oxygen(HBO) on levels of IL-2,TNF-α,IL-4,and IL-10 in allogenic bone marrow transplantation(BMT) and to study the mechanism of HBO antagonizing acute graft-versus-host disease(aGVHD).Methods:The recipient mice were exposed to total body radiation of 1 800 cGy for 10 hours.The HBO group was treated with HBO 3 days before BMT and 2 weeks after BMT.Levels of these cytokines were determined by using ELISA method.Results:All mice in the control group suffered from aGVHD,but none in HBO group.Compared with the control group,levels of IL-2 and TNF-α in HBO group decreased significantly( P 0.05),and levels of IL-4 and IL-10 increased significantly( P 0.05).Conclusion:Hyperbaric oxygen can prevent aGVHD.And the mechanism is relevant to the effect of HBO on the cytokines." @default.
- W2356179968 created "2016-06-24" @default.
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- W2356179968 date "2004-01-01" @default.
- W2356179968 modified "2023-09-25" @default.
- W2356179968 title "Effect of cytokines on hyperbaric oxygen antagonizing acute graft-versus-host disease" @default.
- W2356179968 hasPublicationYear "2004" @default.
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