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- W2356195416 abstract "Objective: To explore the effects of cutaneous formalin(FM) injection of non-inflammatory dose on the activation of vanilloid receptor type 1(VR1) in mice.Methods: KM mice were randomly divided into 3 groups: FM group,capsaicin(CAP) group and capsazepine(CPZ) group.The licking time of the injected paws within 5 min after injection was recorded and considered as an index of pain.Results: 0.025% FM and 200μmol/L CAP were optimal concentrations of the pain reagent,which could evoke painful sensation without inflammation.1μmol/L CPZ had obvious anti-nociceptive effects on the FM-and CAP-induced pain.Results: Pain induced by non-inflammatory dose of FM in peripheral was possibly mediated by VR1." @default.
- W2356195416 created "2016-06-24" @default.
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- W2356195416 date "2006-01-01" @default.
- W2356195416 modified "2023-09-25" @default.
- W2356195416 title "THE ACTIVATION OF CUTANEOUS VR1 IN MICE BY FORMALIN OF NON-INFLAMMATORY DOSE" @default.
- W2356195416 hasPublicationYear "2006" @default.
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