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- W2356211085 abstract "Objective To evaluate the effect and safety of Qinggan Lishi Decoction(decoction for clearing heat and dissolving damp) on chronic hepatitis B with liver and gallbladder damp-heat syndrome in TCM through a randomized controlled trial of small-sized samples.Methods Seventy-five subjects met the designed criteria were randomized into a treatment group and a control group.The treatment group,34 cases,was administered Chinese medicine Qinggan Lishi Decoction and Lamivudine tablets,while the control group,41 cases,was administered Compound Glycyrrhizin tablets and Lamivudine tablets.Both groups were treated for 4 weeks.Changes in visual analogue scores(VAS) of independent symptoms and general symptomatic experience,level of alanine aminotransferase(ALT),viral markers and quantitative value of HBV DNA of the two groups were observed,and the adverse events were monitored in the whole process of trial.Results After treatment,the VAS of independent symptoms and general symptomatic experience and level of ALT were decreased in both groups.The VAS of general symptomatic experience of the treatment group in the 2nd,3rd,and 4th week was significantly lower than that of the control group(P0.05 or P0.01),and the level of ALT in the 3rd week was significantly lower than that of the control group(P0.05).Compared with before treatment,in the 12th week of continuous administration of Lamivudine tablets,the differential value of HBV DNA quantity of the experimental group was significantly higher than that of the control group(P0.05).No severe adverse events occurred during the whole trial.Conclusion Qinggan Lishi Decoction is possibly beneficial to hepatic symptoms,virus load,and liver function of those patients with chronic hepatitis B in TCM syndrome of liver and gallbladder damp-heat." @default.
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- W2356211085 date "2011-01-01" @default.
- W2356211085 modified "2023-09-27" @default.
- W2356211085 title "Clinical Observation on Qinggan Lishi Decoction plus Lamivudine Tablets in the Treatment of Chronic Hepatitis B with Liver and Gallbladder Damp-heat Syndrome: A Report of 34 Cases" @default.
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