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- W2356212869 abstract "Objective This study was designed to investigate the biological characteristics of anorectal melanoma and the significance of radical operation for its treatment. MethodBZA retrospective analysis was made of the clinical and pathological features as well as the results of surgical treatment of 29 cases with anorectal melanoma collected from 1965 to 1995 in Cancer Hospital of Chinese Academy of Medical Sciences. Results There were 19 females and 10 males with their mean age of 50 years.Twentythree out of the 29 cases underwent curative resection (Miles' operation), recurrences developed in 17 (74%) cases with major recurrence pattern of distant metastasis. Only lymph node metastasis influenced the relapse of these patients when analyzing variables such as gender, tumor size, melanin, invasive depth and lymph node spread in terms of prognosis. The remaining six patients were submitted to palliative surgery.The overall postoperative five year's survival rate of all patients and of that received curative resection were 29% and 37% respectively. Six unresectable patients died of their disease at a median of 135 months. HZ Conclusion anorectal melanoma is an aggressive malignant tumor with poor prognosis even though radical resection was done. It was even worse when lymph nodes were involved at the time of operation." @default.
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- W2356212869 date "1999-07-25" @default.
- W2356212869 modified "2023-09-26" @default.
- W2356212869 title "Primary malignant melanoma of the anorectum" @default.
- W2356212869 hasPublicationYear "1999" @default.
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