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- W2356216242 abstract "Objective To explore the effect of autologous blood transfusion on cytoimmunity function during cardiac operation. Methods Two hundred patients undertaken selective cardiac operation from August 2008 to October 2012 were divided into observation group(120 cases) and control group(80 cases). The observation group received autologous blood transfusion and the control group was given homologous transfusion. T lymphocyte subsets and natural killer(NK) cell counts in blood samples were detected by flow cytometry before operation and one and five days after operation. Results The CD3+,CD4 +,CD4 + / CD8 +,NK cell of the observation group and control group on the first day of post-operation were(0. 7012 ± 0. 085 6),(0. 374 8 ± 0. 058 9),(1. 64 ± 0. 23),(0. 152 4 ± 0. 059 8) and(0. 632 9 ± 0. 081 6),(0. 302 3 ± 0. 0675),(1. 23 ± 0. 28),(0. 144 2 ± 0. 045 2),respectively. The cell counts of pre-operation in both groups were(0. 779 6 ±0. 112 4),(0. 446 2 ± 0. 080 1),(1. 73 ± 0. 24),(0. 213 4 ± 0. 065 2) and(0. 763 2 ± 0. 089 5),(0. 453 1 ± 0. 070 1),(1. 65 ± 0. 31),(0. 186 9 ± 0. 054 7)(P 0. 05),respectively. The cell counts on the first day of post-operation of both groups demonstrated a decreasing trend after operation. The above parameters of the observation group were significantly higher than those of the control group on first day of post-operation(P 0. 05). There were no significant differences in CD3 +,CD4 +,CD4 + / CD8 + and NK cell on the fifth day of post-operation when comparing the control group with the observation group before operation(P 0. 05). However,the CD3 +,CD4 +,CD4 + / CD8 + and NK cell of the control group on the fifth day of the post-operation were(0. 589 7 ± 0. 070 2),(0. 276 8 ± 0. 051 2),(1. 01 ± 0. 32),and(0. 121 4 ± 0. 056 9),which were significantly lower than those of the control group before operation(P 0. 05). Conclusion Intra-operative autologous blood transfusion had less inhibitory effect on cytoimmunity than homologous transfusion. Patients who had received autologous blood transfusion had a rapid recovery of cytoimmunity." @default.
- W2356216242 created "2016-06-24" @default.
- W2356216242 creator A5064518750 @default.
- W2356216242 date "2014-01-01" @default.
- W2356216242 modified "2023-09-23" @default.
- W2356216242 title "Effect of autologous blood transfusion on cytoimmunity function in patients undergoing cardiac operation" @default.
- W2356216242 hasPublicationYear "2014" @default.
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