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- W2356217103 abstract "OBJECTIVE:To study protective effects of Ketorolac tromethamine ophthalmic gel against Staphylococcus aureus corneal ulcer in rabbits. METHODS:S. aureus corneal ulcer in rabbits model was induced by corneal substance layer inoculation,and then divided into model group,positive control group(Clarithromycin ophthalmic gel),gel high-dose,medium-dose and low-dose groups(Ketorolac tromethamine ophthalmic gel 120,80,40 mg/ml),with 20 rabbits in each group. They were given relevant medicine,once a day for 2 weeks. The keratopathy of rabbits was observed;the clinical efficacy and keratopathy score were compared. The change of ratina was observed under micrescope. RESULTS:Compared with model group,the keratopathy score decreased while total effective rate increased in positive control group and gel groups after medication,and the effects of gel high-dose and low-dose groups were significantly lower than that of positive control group,with statistical significance(P0.05).The retina of rabbits had not affected by the experiment. CONCLUSIONS:Ketorolac tromethamine ophthalmic gel has protective effect against S. aureus corneal ulcer in rabbits." @default.
- W2356217103 created "2016-06-24" @default.
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- W2356217103 date "2015-01-01" @default.
- W2356217103 modified "2023-09-25" @default.
- W2356217103 title "Protective Effects of Ketorolac Tromethamine Ophthalmic Gel against Staphylococcus aureus Corneal Ulcer in Rabbits" @default.
- W2356217103 hasPublicationYear "2015" @default.
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