Matches in SemOpenAlex for { <https://semopenalex.org/work/W2356285281> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2356285281 endingPage "94" @default.
- W2356285281 startingPage "889" @default.
- W2356285281 abstract "To provide the acute toxicity data of cowpea trypsin inhibitor (CpTI) using recombinant protein purified from E. coli.Recombinant CpTI protein was expressed and purified from E. coli. Bacterial recombinant plasmid was transformed into E. coli and the transformed cells were induced with IPTG. The expressed CpTI protein was purified by hydrophobic interaction chromatography and anion exchange chromatography. Sixty mice, randomly assigned to 6 groups, were administrated 10.0, 4.64, 2.15 and 1.00 g/kg BW of CpTI or 5.00 g/kg BW of BSA control protein or sterile water respectively by oral gavage.All animals survived with no significant change in body weight and food consumption throughout the study. Macroscopic necropsy examination on day 15 revealed no gross pathological lesions in any of the animals. The maximum tolerated dose (MTD) of CpTI was more than 10.0 g/kg body weight in mice.No toxicity of CpTI protein was found in ICR mice model." @default.
- W2356285281 created "2016-06-24" @default.
- W2356285281 creator A5014080989 @default.
- W2356285281 creator A5025971885 @default.
- W2356285281 creator A5050727001 @default.
- W2356285281 creator A5053204257 @default.
- W2356285281 creator A5056767734 @default.
- W2356285281 creator A5087884556 @default.
- W2356285281 date "2012-11-01" @default.
- W2356285281 modified "2023-09-27" @default.
- W2356285281 title "[Large-scale purification and acute toxicity of cowpea trypsin inhibitor]." @default.
- W2356285281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23424862" @default.
- W2356285281 hasPublicationYear "2012" @default.
- W2356285281 type Work @default.
- W2356285281 sameAs 2356285281 @default.
- W2356285281 citedByCount "0" @default.
- W2356285281 crossrefType "journal-article" @default.
- W2356285281 hasAuthorship W2356285281A5014080989 @default.
- W2356285281 hasAuthorship W2356285281A5025971885 @default.
- W2356285281 hasAuthorship W2356285281A5050727001 @default.
- W2356285281 hasAuthorship W2356285281A5053204257 @default.
- W2356285281 hasAuthorship W2356285281A5056767734 @default.
- W2356285281 hasAuthorship W2356285281A5087884556 @default.
- W2356285281 hasConcept C104317684 @default.
- W2356285281 hasConcept C116263406 @default.
- W2356285281 hasConcept C178790620 @default.
- W2356285281 hasConcept C181199279 @default.
- W2356285281 hasConcept C185592680 @default.
- W2356285281 hasConcept C206967267 @default.
- W2356285281 hasConcept C2776351012 @default.
- W2356285281 hasConcept C2780340462 @default.
- W2356285281 hasConcept C29730261 @default.
- W2356285281 hasConcept C40767141 @default.
- W2356285281 hasConcept C55493867 @default.
- W2356285281 hasConcept C86803240 @default.
- W2356285281 hasConcept C98274493 @default.
- W2356285281 hasConceptScore W2356285281C104317684 @default.
- W2356285281 hasConceptScore W2356285281C116263406 @default.
- W2356285281 hasConceptScore W2356285281C178790620 @default.
- W2356285281 hasConceptScore W2356285281C181199279 @default.
- W2356285281 hasConceptScore W2356285281C185592680 @default.
- W2356285281 hasConceptScore W2356285281C206967267 @default.
- W2356285281 hasConceptScore W2356285281C2776351012 @default.
- W2356285281 hasConceptScore W2356285281C2780340462 @default.
- W2356285281 hasConceptScore W2356285281C29730261 @default.
- W2356285281 hasConceptScore W2356285281C40767141 @default.
- W2356285281 hasConceptScore W2356285281C55493867 @default.
- W2356285281 hasConceptScore W2356285281C86803240 @default.
- W2356285281 hasConceptScore W2356285281C98274493 @default.
- W2356285281 hasIssue "6" @default.
- W2356285281 hasLocation W23562852811 @default.
- W2356285281 hasOpenAccess W2356285281 @default.
- W2356285281 hasPrimaryLocation W23562852811 @default.
- W2356285281 hasRelatedWork W1234218055 @default.
- W2356285281 hasRelatedWork W1964484959 @default.
- W2356285281 hasRelatedWork W2072955138 @default.
- W2356285281 hasRelatedWork W2349192472 @default.
- W2356285281 hasRelatedWork W2352906756 @default.
- W2356285281 hasRelatedWork W2356285281 @default.
- W2356285281 hasRelatedWork W2389039755 @default.
- W2356285281 hasRelatedWork W2414453160 @default.
- W2356285281 hasRelatedWork W3130638756 @default.
- W2356285281 hasRelatedWork W3201248417 @default.
- W2356285281 hasVolume "41" @default.
- W2356285281 isParatext "false" @default.
- W2356285281 isRetracted "false" @default.
- W2356285281 magId "2356285281" @default.
- W2356285281 workType "article" @default.