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- W2356286809 abstract "The change of water cluster structure of CuCl 2 aqueous solution was determined in this paper by density and viscosity of CuCl 2 aqueous solution,which discovered that the freezing / thawing disposal in CuCl 2 aqueous solution resulted in obvious decrease of density and increase of viscosity.It can be speculated that the results are the formation of smaller water cluster structure by hydrogen bond and the increase of water association of CuCl 2 aqueous solution after freezing / thawing disposal.The interaction between CuCl 2 aqueous solution before / after freezing / thawing disposal and BSA were studied by laser confocal Raman microspectroscopy,which indicated that interaction between CuCl 2 and BSA caused the shift of BSA amideⅠbands,the increase of β sheets,the change of the configuration of disulfide bonds,and the alteration of the microenvironment of tyrosine.If BSA bound with CuCl 2 aqueous solution after freezing / thawing disposal,then the degree which BSA amideⅠ band shifted was smaller,and the effect on the microenvironment of tyrosine was lower than that of CuCl 2 aqueous solution without freezing / thawing disposal.It can be concluded that the freezing / thawing disposal in CuCl 2 aqueous solution can cause the weakened effect of the interaction with BSA,and this weakened effect was associated with the change of water cluster structure." @default.
- W2356286809 created "2016-06-24" @default.
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- W2356286809 date "2013-01-01" @default.
- W2356286809 modified "2023-09-25" @default.
- W2356286809 title "Raman spectroscopic study on effect of freezing disposal on the interaction of CuCl_2 and bovine serum albumin" @default.
- W2356286809 hasPublicationYear "2013" @default.
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