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- W2356336162 abstract "Objective To observe plasma homocysteine(Hcy) level changes in elderly patients with vascular dementia(VD) and therapeutic effect of Mecobalamin combined with folic acid intervention.Methods 51 VD patients were as treatment group.60 healthy volunteers were as control group.The changes of plasma homocysteine,folic acid and VitB12 level in VD patients were measured.The changes of Mini-Mental State Examination(MMSE) score,plasma homocysteine,folic acid and VitB12 level were observed before and after VD patients were treated by Mecobalamin combined with folic acid.Results There were obvious differences between two groups on the levels of plasma homocysteine,folic acid and VitB12(P0.01).There were significant differences between before and after treatment on the levels of plasma homocysteine,folic acid and VitB12 in treatment group(P0.01).There was no significant difference on MMSE score(P0.05).Conclusion The plasma Hcy levels in VD was significantly higher than that in healthy,folic acid and VitB12 level was lower,Mecobalamin combined with folic acid can apparently ease high Hcy hyperlipidemia status in patients." @default.
- W2356336162 created "2016-06-24" @default.
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- W2356336162 date "2012-01-01" @default.
- W2356336162 modified "2023-09-24" @default.
- W2356336162 title "Observation of plasma homocysteine level changes and therapeutic effect in elderly patients with vascular dementia" @default.
- W2356336162 hasPublicationYear "2012" @default.
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