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- W2356351454 abstract "Purpose To investigate the expression pattern of SYT protein in monophasic fibrous synovial sarcoma(MFSS) and to evaluate its potential value in differential diagnosis between MFSS and other spindle cell soft tissue tumors.Methods We detected SYT protein expression in 36 MFSS cases and 32 non-synovial sarcoma including 7 malignant peripheral nerve sheath tumor cases,6 fibrosarcoma cases,4 leiomyosarcoma cases,7 malignant fibrous histiocytoma and 8 solitary fibrous tumor cases.Results Positive staining rate of SYT protein in MFSS was 91.67%(33/36),15 cases showed diffusely and strongly nuclear staining(over 80% of the tumor cells showed nuclear staining)and 12 cases displayed variable degrees of nuclear staining with strong staining in about 50% to 80% of the tumor cells.Positive staining rate of SYT protein in non-synovial sarcoma cases was 59.37%(19/32),6 cases displayed diffusely and strongly nuclear staining,while 7 non-synovial sarcoma cases showed variable degrees of nuclear staining with strong staining in about 50% to 80% of the tumor cells.Conclusions Diffusely and strongly nuclear staining for SYT antibody presents not only in MFSS,but also in other spindle cell soft tissue tumors.Thus SYT antibody alone could not distinguish MFSS from other spindle cell soft tissue tumors." @default.
- W2356351454 created "2016-06-24" @default.
- W2356351454 creator A5008065884 @default.
- W2356351454 date "2009-01-01" @default.
- W2356351454 modified "2023-09-24" @default.
- W2356351454 title "Expression of SYT protein in monophasic fibrous synovial sarcoma and other spindle cell tumors and its value in differential diagnosis" @default.
- W2356351454 hasPublicationYear "2009" @default.
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