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- W2356363114 abstract "Objective To investigate noninvasive parameters or model for diagnosing esophageal and/or gastric fundus varices in patients with liver cirrhosis.Methods Data of 58 patients with liver cirrhosis caused by hepatitis B were collected,34 patients had esophageal and/or gastric varices.All patients were classified according to Child-Pugh grade(32 Child-Pugh-A,13 Child-Pugh-B,13 Child-Pugh-C).The laboratory Variables including coagulation factors and liver function tests were performed.Spleen thickness and portal vein width were measured on ultrasonography.Endoscopy was used to detect the esophageal and/or gastric fundus varices.Results Patients with liver cirrhosis were divided into varices group and non-varices group,differences in platelet,prothrombin time activity(PTA),activated partial thromboplastin time,coagulation Factors Ⅱ,Ⅴ,Ⅶ,Ⅷ,Ⅸ,Ⅹ,fibrinogen,D-dimer,liver function factors(prealbumin,albumin,total bilirubin,total bile acid,cholinesterase),spleen thickness,and portal vein width between two groups were statistically significant(P0.05).Through Logistic regression analysis,PTA,portal vein width,spleen thickness were the factors which help discriminating esophageal and/or gastric fundus varices existing or not in patients with liver cirrhosis,Logit P=12.280×portal vein width+2.901×spleen thickness-0.145×PTA-17.746,predicting accuracy was 68.0%,sensitivity was 69.2%,specificity was 66.6%.Patients classified into Child-Pugh A were also divided into varices group and non-varices group,differences in PTA,D-dimer,coagulation factor Ⅱ,Ⅸ,platelet,spleen thickness,portal vein width between two group were statistically significant(P0.05).Conclusion PTA,portal vein width,and spleen thickness may help discriminate presence or absence of esophageal and/or gastric fundus varices in patients with liver cirrhosis." @default.
- W2356363114 created "2016-06-24" @default.
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- W2356363114 date "2011-01-01" @default.
- W2356363114 modified "2023-09-26" @default.
- W2356363114 title "Noninvasive parameters for diagnosing esophageal and/or gastric fundus varices in patients with liver cirrhosis" @default.
- W2356363114 hasPublicationYear "2011" @default.
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