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- W2356374017 abstract "Kucha(Camellia kucha) is a special wild tea plant containing a great amount of theacrine(1,3,7,9-tetramethyluric acid) besides caffeine and theobromine.Acute toxicity and sedative/hypnotic activity of Kucha were studied.The result showed that the LD50 of Kucha was more than 21.50 gkg bw,suggested that the water extract of Kucha had no toxicity under our experimental conditions.Theacrine could obviously prolong the sleeping time of mice induced by pentobarbital sodium,while caffeine had the opposite exciting effect.When the contents of these two components were about similar in Kucha,no significant sedative and hypnotic effects or exciting effect was observed.However,when The contents of theacrine was 3 fold higher than that of caffeine,Kucha showed potent sedative and hypnotic properties." @default.
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- W2356374017 date "2010-01-25" @default.
- W2356374017 modified "2023-09-25" @default.
- W2356374017 title "Primary Studies on Acute Toxicity and Sedative/hypnotic Activity of Camellia kucha" @default.
- W2356374017 hasPublicationYear "2010" @default.
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