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- W2356416200 abstract "AIM: To study the effects of Euphorbia coadministration with Glycyrrhiza on the mRNA,protein expression and activity of cytochrome P450 3A2 (CYP3A2) in rats.METHODS: The expression of CYP3A2 mRNA was detected by semi-quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) and the expression of CYP3A2 protein was detected by Western Blotting.The activity of CYP3A2 was analyzed by erythromycin demethylation method.RESULTS: The expression of CYP3A2 mRNA and CYP3A2 protein,and the activity of CYP3A2 were higher in Euphorbia group than those in the other groups.CONCLUSION: Euphorbia coadministration with Glycyrrhiza may have some interaction based on CYP3A2." @default.
- W2356416200 created "2016-06-24" @default.
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- W2356416200 date "2005-01-01" @default.
- W2356416200 modified "2023-09-27" @default.
- W2356416200 title "Effects of Euphorbia coadministration with Glycyrrhiza on CYP3A2 in rat" @default.
- W2356416200 hasPublicationYear "2005" @default.
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