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- W2356445866 abstract "Objective To summarize the experience of intracytoplasmic sperm injection(ICSI) following preparation in cases of cryptozoospermia and severe asthenospermia. Methods Two hundred and eighty-three cycles with cryptozoospermia and 65 cycles with severe asthenospermia underwent appropriate drug therapy prior to the ICSI procedure.Fifty-two ICSI procedures in which donor spermatozoa was used were served as controls.Details of each ICSI procedure were recorded,as well as subsequent fertilization and pregnancy rates. Results Due to insufficient patient spermatozoa,15 cycles with cryptozoospermia and 3 cycles with severe asthenospermia required the combination of donor and patients' spermatozoa for ICSI.The rest of the ICSI procedures used spermatozoa from a single source.There were significant differences in fertilization rates between the cryptozoospermia and controls(77.4% vs 85.1%,P=0.001),while the fertilization rates of the group with severe asthenospermia were not significantly different from those of the control group(81.2% vs 85.1% P=0.131).There was no significant difference in pregnancy rates between the groups of cryptozoospermia and controls(40.7% vs 38.8%,P=0.805) and between the groups of severe asthenospermia and controls(31.3% vs 38.8%,P=0.404). Conclusion In patients with cryptozoospermia and severe asthenospermia,the combination of skillful ICSI techniques and appropriate preparation before ICSI may achieve fertilization rates and pregnancy rates slightly lower than or similar to the procedures done with normal sperm." @default.
- W2356445866 created "2016-06-24" @default.
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- W2356445866 date "2008-01-01" @default.
- W2356445866 modified "2023-09-25" @default.
- W2356445866 title "Preoperative preparation and outcome analysis of ICSI for cryptozoospermia and severe asthenospermia" @default.
- W2356445866 hasPublicationYear "2008" @default.
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