Matches in SemOpenAlex for { <https://semopenalex.org/work/W2356553996> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2356553996 abstract "Chitin deacetylases (CDAs) are important enzymes that regulate ecdysis physiology,organ formation and anti-pathogen immunity during insect development.The full length cDNA of CDAs in Bombyx mori was cloned using rapid amplification of cDNA ends (RACE) method and its mRNA was identified to have two splicing variants,designated as BmCDA1 and BmCDA2,both of which were formed predominantly by exon skipping.Bioinformatic analysis to gene structure of BmCDAs revealed that BmCDAs are composed of six exons and five introns.The deduced amino acid sequence of both BmCDA1 and BmCDA2 contain chitin deacetylase domain (CDA),chitin binding domain (ChBD) and low-density lipoprotein receptor class A (LDLa) domain.However,partial divergence of the amino acid residues of BmCDA1 and BmCDA2 was discovered in the chitin binding domain.Insect CDA-like proteins are classified into five orthologous groups based on phylogenetic analysis and the presence of functional domains.BmCDA1 and BmCDA2 belonged to Group Ⅰ,which are typical insect CDA proteins comp-rising of all three functional domains.Real time PCR analysis revealed that expression of BmCDAs varied not only at different developmental stages but also in different tissues.Its expression level was the highest before and after molting/ecdysis of the larvae and pupae,and was the lowest on the second day after molting of the larvae.During ecdysis,the expression level of BmCDA in tissues like epidermis,trachea,and midgut etc which have dramatic morphological changes was obviously higher than that in tissues like middle silk gland and fat body which have little morphological change.Besides,BmCDA1 was predominantly expressed at the developmental stages or in the tissues which had high expression levels of BmCDAs,while BmCDA2 was predominantly expressed in tissues which had low expression levels of BmCDAs.These results would facilitate further investigations on functions and regulatory mechanism of CDA genes." @default.
- W2356553996 created "2016-06-24" @default.
- W2356553996 creator A5001089259 @default.
- W2356553996 date "2010-01-01" @default.
- W2356553996 modified "2023-09-25" @default.
- W2356553996 title "Gene Structure,mRNA Alternative Splicing and Expression Pattern of Chitin Deacetylases in Silkworm,Bombyx mori" @default.
- W2356553996 hasPublicationYear "2010" @default.
- W2356553996 type Work @default.
- W2356553996 sameAs 2356553996 @default.
- W2356553996 citedByCount "1" @default.
- W2356553996 countsByYear W23565539962014 @default.
- W2356553996 crossrefType "journal-article" @default.
- W2356553996 hasAuthorship W2356553996A5001089259 @default.
- W2356553996 hasConcept C104317684 @default.
- W2356553996 hasConcept C153911025 @default.
- W2356553996 hasConcept C173758957 @default.
- W2356553996 hasConcept C187882448 @default.
- W2356553996 hasConcept C194583182 @default.
- W2356553996 hasConcept C19924922 @default.
- W2356553996 hasConcept C2778332815 @default.
- W2356553996 hasConcept C2778487026 @default.
- W2356553996 hasConcept C2779732960 @default.
- W2356553996 hasConcept C2781088250 @default.
- W2356553996 hasConcept C36823959 @default.
- W2356553996 hasConcept C41905685 @default.
- W2356553996 hasConcept C50724178 @default.
- W2356553996 hasConcept C54355233 @default.
- W2356553996 hasConcept C55493867 @default.
- W2356553996 hasConcept C59822182 @default.
- W2356553996 hasConcept C86803240 @default.
- W2356553996 hasConcept C91151737 @default.
- W2356553996 hasConceptScore W2356553996C104317684 @default.
- W2356553996 hasConceptScore W2356553996C153911025 @default.
- W2356553996 hasConceptScore W2356553996C173758957 @default.
- W2356553996 hasConceptScore W2356553996C187882448 @default.
- W2356553996 hasConceptScore W2356553996C194583182 @default.
- W2356553996 hasConceptScore W2356553996C19924922 @default.
- W2356553996 hasConceptScore W2356553996C2778332815 @default.
- W2356553996 hasConceptScore W2356553996C2778487026 @default.
- W2356553996 hasConceptScore W2356553996C2779732960 @default.
- W2356553996 hasConceptScore W2356553996C2781088250 @default.
- W2356553996 hasConceptScore W2356553996C36823959 @default.
- W2356553996 hasConceptScore W2356553996C41905685 @default.
- W2356553996 hasConceptScore W2356553996C50724178 @default.
- W2356553996 hasConceptScore W2356553996C54355233 @default.
- W2356553996 hasConceptScore W2356553996C55493867 @default.
- W2356553996 hasConceptScore W2356553996C59822182 @default.
- W2356553996 hasConceptScore W2356553996C86803240 @default.
- W2356553996 hasConceptScore W2356553996C91151737 @default.
- W2356553996 hasLocation W23565539961 @default.
- W2356553996 hasOpenAccess W2356553996 @default.
- W2356553996 hasPrimaryLocation W23565539961 @default.
- W2356553996 hasRelatedWork W1964446688 @default.
- W2356553996 hasRelatedWork W1985796363 @default.
- W2356553996 hasRelatedWork W1987081580 @default.
- W2356553996 hasRelatedWork W1987682648 @default.
- W2356553996 hasRelatedWork W2020147836 @default.
- W2356553996 hasRelatedWork W2045210872 @default.
- W2356553996 hasRelatedWork W2104980840 @default.
- W2356553996 hasRelatedWork W2106318619 @default.
- W2356553996 hasRelatedWork W2123205103 @default.
- W2356553996 hasRelatedWork W2153984902 @default.
- W2356553996 hasRelatedWork W2347468839 @default.
- W2356553996 hasRelatedWork W2354867095 @default.
- W2356553996 hasRelatedWork W2366959506 @default.
- W2356553996 hasRelatedWork W2368974124 @default.
- W2356553996 hasRelatedWork W2373143364 @default.
- W2356553996 hasRelatedWork W2384464450 @default.
- W2356553996 hasRelatedWork W2388419646 @default.
- W2356553996 hasRelatedWork W2392299129 @default.
- W2356553996 hasRelatedWork W2766804518 @default.
- W2356553996 hasRelatedWork W2804923728 @default.
- W2356553996 isParatext "false" @default.
- W2356553996 isRetracted "false" @default.
- W2356553996 magId "2356553996" @default.
- W2356553996 workType "article" @default.