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- W2356556265 abstract "Purpose To investigate the influence of low-dose ultrasound(LDUS) mediated microbubble on the increasing Evans blue(EB) concentration in rat prostate. Materials and Methods Sixty male Sprague-Dawley(SD) rats were divided into control group, EB-only group, microbubble-only group, LDUS after EB group and LDUS before EB group. Each group had 12 rats. The control group was injected with 10 ml/kg sodium chloride, EB-only group was given 50 mg/kg EB without LDUS mediation, microbubbleonly group was given with microbubble contrast agent without LDUS mediation, LDUS after EB group was given LDUS mediation right after EB and microbubble injection, the LDUS before EB group was LDUS medicated before EB and microbubble injection. Concentration of EB in prostate tissue was measured homogenated. Results EB concentration of rat prostate in EB group was statistically higher than the control group and microbubble-only group(t=4.157 and 4.357, P0.01); that in LDUS after EB group was higher than the EB group(t=2.438, P0.05); but that in LDUS before EB group was significantly lower than LDUS before EB group(t=2.761, P0.05); no statistical difference in EB concentration was observed between LDUS after EB group and EB group(t=0.684, P0.05). Conclusion Low-dose ultrasound-mediated microbubble can increase in the EB concentration in rat prostate." @default.
- W2356556265 created "2016-06-24" @default.
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- W2356556265 date "2014-01-01" @default.
- W2356556265 modified "2023-09-28" @default.
- W2356556265 title "Influence of Low-dose Ultrasound-mediated Micro-bubble on the Evans Blue Concentration in the Rat Prostate" @default.
- W2356556265 hasPublicationYear "2014" @default.
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