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- W2356559852 abstract "The results of our preliminary observations using the manometric method are summarized as follows:(1) The endogenous respiration of erythrocytes was determined in 15 young male and 15 young female subjects. Their oxygen consumption rates within the first hour were respectively 0.011±0.001 and 0.021±0.002/μl/hr/mg dry weight. The data for the female group were significantly higher than those for the male group. However, the oxygen consumption rate for the second hour showed no significant difference between the two groups. The addition of glucose and traces of methylene blue increased the rate of endogenous oxygen consumption in erythrocytes nearly sevenfold.(2) The utilization of 9 carbohydrates (4 hexoses, 3 pentoses and 2 disaccharides) by the erythrocyte suspensions was compared in 86 young adults. The approximate order of oxygen consumption rate in erythrocytes was hexosespentosesdisaccharides. Glucose, galactose and fructose were utilized quite well, their effects on the rate of oxygen consumption of erythrocytes differed very significantly from those of the pentose and disaccharide groups [glucose (galactose)fructoseribose (mannose)]. The uptake rates of ribose and mannose by the erythrocytes were somewhat lower, the rate of oxygen consumption of these 2 sugars showed no significant difference in comparison with xylose, arabinose, sucrose and lactose.(3) The influence of some enzyme inhibitors upon glycolysis and oxygen consumption of erythrocyte suspensions in the presence of 3 hexoses and ribose was investigated in healthy Chinese adults. The inhibition of lactic acid production and oxygen consumption was the strongest in the case of iodoacetic acid (IAA), with sodium fluoride (NaF) ranking next, and arsenite third. Arsenate and p-chloromercuribenzoate (PCMB) respectively promoted erythrocyte glycolysis prominently and moderately on the one hand; but inhibited the rate of oxygen consumption in erythrocytes slightly and moderately on the other hand.(4) In connection with the results of our experiments, the possible mechanism of methylene blue in promoting oxygen consumption and the effect of some enzyme inhibitors on glycolysis and oxygen consumption in erythrocytes have been briefly discussed." @default.
- W2356559852 created "2016-06-24" @default.
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- W2356559852 date "1976-01-01" @default.
- W2356559852 modified "2023-09-25" @default.
- W2356559852 title "THE UTILIZATION OF SOME MONOSACCHARIDES AND DISACCHARIDES BY THE ERYTHROCYTES OF HEALTHY CHINESE ADULTS" @default.
- W2356559852 hasPublicationYear "1976" @default.
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