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- W2356616928 abstract "Objective:To evaluate the clinical effect of diltiaxzem (Herbesser) infusion in OPCAB. Methods:51 Patients with coronary heart disease who underwent OPCAB during Apr.2007 and Mar.2008 were randomly divided into 2 groups:test group (n=26) and control group (n=25). During the peri-opertative period,Herbesser and Isosorbide Mononitrate was given in the control group. Serum CKMb,cTnT,heart rate PR-interval,ORS wave,QT interval,blood pressure,blood routine test and blood biochemistry marker were tested after operation and compared. Results:Of the 51 patients,no one died,or had post-operation complications. No differences of the incidence of arrhythmia,or hemodynamics were observed. Serum CKMb and cTnT concentrations were significantly lower at both 24hrs and 48 hrs after operation in the test group (P0.05),but not those at 72 hrs post-operatively. There was a slight and insignificant decrease of heart rate,systolic and dilatic blood pressure in the patients from the test group at 72 hrs post-operatively (P0.05). PR interval and QT interval were slightly longer in the test group,but no statistical significance was attained. Conclusion:Joint use of Herbesser with Isosorbide Mononitrate during peri-operation period of OPCAB showed no serious side effect,but reduced myocardial oxygen consumption markdly,thus provided better myocardial protection." @default.
- W2356616928 created "2016-06-24" @default.
- W2356616928 creator A5056742440 @default.
- W2356616928 date "2009-01-01" @default.
- W2356616928 modified "2023-09-23" @default.
- W2356616928 title "Application of Herbesser in OPCAB-A Randomized Perspective Clinical Trial" @default.
- W2356616928 hasPublicationYear "2009" @default.
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