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- W2356707094 abstract "Objective:To study the clinical significance of the quantitative detection and genotype of HCV-RNA. Methods:Fluorescent quantitative PCR methods were used to detect 212 cases of anti-HCV or HCV-RNA positive samples,the concentrations of anti-HCV and ALT were detected by the third generation ELISA and automatic biochemistry analyzer. The HCV-RNA genotypes of 78 cases were detected by RT-PCR. Results:Among 212 samples,HCV-RNA(+)/anti-HCV(+) both positive results were 155 cases. Positive coincident rate was 73.1%(155/212).It was positive correlation between quantity of HCV-RNA and the number of anti-HCV positive samples(r=0.92,P0.05). It was positive correlation between the quantity of HCV-RNA and the number of samples with abnormal ALT(r=0.57,P0.05).78 samples were genotyped:92.3% were HCVⅡ/1b. Conclusion:There was limitation in both HCV-RNA and anti-HCV methods. It was more accurately to using two methods to diagnosing HCV. People in our country were mainly infected by HCV Ⅱ/1b.Diagnosis of HCV genotype could provide scientific basis for drug selection." @default.
- W2356707094 created "2016-06-24" @default.
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- W2356707094 date "2006-01-01" @default.
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- W2356707094 title "Study on HCV-RNA quantitative detection and genotype" @default.
- W2356707094 hasPublicationYear "2006" @default.
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