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- W2356733206 abstract "[Objective] Setting up a method to detect YMDD mutation during lamivudine therapy and study the application pull the rice man settles the treatment and did not use the initial stages in hepatitis in type in B of the medicine treatment the sufferer the circumstance of the inside YMDD variation stub occurrence.[Methods] The application comes together with the real time PCR method to the early hair in liver in B for having not yet any medicine treatment sufferer,50 usages pulls the rice man settles the sufferer who cure a year,50 usages pulls the sufferer that rice man settle two years in treatment to pull with 20 usages the rice man settle with the interferon sufferer of uniting two years in treatment at the same time the examination that proceed the YMDD variation stub.[Results] Pass to solve the curvilinear analysis to the liquate linear,examine the 2 examples :YMDD variation stub in earlier in liver in B that had not yet any treatment sufferer,occupy 6.67%;Pulling the rice man settle the sufferer who cure to examine the 13 examples :YMDD variation stub in a year,occupying 26.00%;Pulling the rice man settles two years in treatment to examine the 25 examples :YMDD variation stub in the sufferer,occupying 50.00%,pulling the rice man settle to examine the 9 examples :YMDD variation stub with interferon in the sufferer of uniting the treatment,occupying 45.00%.[Conclusion] Exsits namely in had not yet any medicine treatment of B liver sufferer YMDD variation stub,and pull along with the usage the rice man settles the horary extension at increase continuously,and in association with use the medicine and can't reduce the occurrence of the variation stub,therefore to B liver the sufferer proceeds in use medicine front,and use medicine process the YMDD variation stub examination is very necessary.The method described here provides a convenient,rapid,accurate and inexpensive way to monitor YMDD mutation during lamivudine therapy." @default.
- W2356733206 created "2016-06-24" @default.
- W2356733206 creator A5055708357 @default.
- W2356733206 date "2007-01-01" @default.
- W2356733206 modified "2023-09-24" @default.
- W2356733206 title "Applicate method of real time PCR to detect YMDD variation in HBV" @default.
- W2356733206 hasPublicationYear "2007" @default.
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