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- W2356849516 abstract "Objective To explore the expression and significance of TNF-α,IL-6,NF-κB in alcoholic liver disease(ALD) patients and the role of apoptosis in ALD.Methods Serum levels of TNF-α,IL-6,and NF-κB of 54 ALD patients and 31 healthy subjects were analyzed using enzyme-linked immunosorbent assay(ELISA) method,with the role these cytokines played in the pathogenesis of ALD.Levels of GGT,aspartate aminotransferase(AST),and alanine aminotransferase(ALT)were measured by an automatic biochemical analyzer.Results(1)Serum levels of TNF-α,IL-6,NF-κB,GGT,AST,and ALT were significantly higher in the ALD group than in the control group(P0.05);(2) Positive correlations existed among serum levels of TNF-α,IL-6,and GGT(P0.05).Conclusion As inflammatory factors and nuclear transcription factors,TNF-α,IL-6,NF-κB play important roles in the pathogenesis of ALD and combination detection could provide certain references in reading the liver inflammatory responses and hepatocyte apoptosis among ALD patients." @default.
- W2356849516 created "2016-06-24" @default.
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- W2356849516 date "2011-01-01" @default.
- W2356849516 modified "2023-09-23" @default.
- W2356849516 title "The Expression and Significance of TNF-α,IL-6,and NF-κB in the Serum of Patients with Alcoholic Liver Disease" @default.
- W2356849516 hasPublicationYear "2011" @default.
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