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- W2356897773 abstract "Lactoferrin(Lf),an iron-binding glycoprotein with various physiological functions,plays an key roles in iron metabolism and transfer.Recently,more and more attentions have been paid to Lf in the treatment of neurodegenerative diseases.This review mainly addressed the iron metabolism in human;iron transport protein-lactoferrin transport system;iron transport is mediated by the transferrin receptor and lactoferrin receptor.The major route of iron transport into brain is transfer-transferrin receptor pathway,the lactoferrin-lactoferrin receptor pathway and other routes are also important for iron transport;the mechanism of iron in cerebral injury,the reason of cerebral injury probably caused by the oxidative stress which iron participate in and the gene of iron metabolism and iron transport mutation or deletion.Finally,the latest advances of Lf in the prevention and treatment of neurodegenerative diseases were summarized.Lactoferrin-modified nanoparticles may be one of the most effective treatment of neurodegenerative diseases." @default.
- W2356897773 created "2016-06-24" @default.
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- W2356897773 date "2013-01-01" @default.
- W2356897773 modified "2023-09-23" @default.
- W2356897773 title "Effect of Lactoferrin on Iron Metabolism and the Application in Neurodegenerative Diseases" @default.
- W2356897773 hasPublicationYear "2013" @default.
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