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- W2356918769 abstract "Objective To observe epithelial sodium channels (ENaC) currents in spermatogenic cells. Method Epithelial sodium channels were obtained in acutely dissociated mouse spermatogenic cells using whole-cell patch clamp. Results The currents were evoked by 200 ms test pulses between -100~+40 mV in 10 mV increments from a holding potential (HP) of -50 mV. Test pulses elicited rapidly activating and non-inactivating Na+ current. Na+ currents amplitude were significantly reduced by adding Amiloride (1 μmol/L) to the external solution, and displayed two kinds of inhibition effects (the ratio of 58.49%±9.82%, 31.44%±5.69%). Conclusion The characteristics of such currents and sensitive to Amiloride all approved that these currents recorded from mouse spermatogenic cells were produced through epithelial sodium channels." @default.
- W2356918769 created "2016-06-24" @default.
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- W2356918769 date "2006-01-01" @default.
- W2356918769 modified "2023-09-24" @default.
- W2356918769 title "Currents Sensitive to Amiloride in Mouse Spermatogenic Cells" @default.
- W2356918769 hasPublicationYear "2006" @default.
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