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- W2356956633 abstract "Objective To determine the acute toxicity(LD-{50}) of “Yao_Tong_Ning” Capsule(YTNC) for oral administration in rats and mice. Methods LD-{50} were tested by Billis method. Results The YTNC was orally administrated in mice of Kunming and BALB/c, rats of SD and wistar,respectively. The LD_(50) of mice of Kunming and BALB/c was (640.44±137.57) mg/kg and (448.37±60.59) mg/kg,respectively. The LD-{50} of female and male was(803.85±163.94.0) mg/kg and(6158.95±1021.70) mg/kg in SD rats, respectively. The LD-{50} of female and male was (861.94±325.00) mg/kg and (5807.57±1300.39) mg/kg in wistar rats, respectively. Conclusion The LD-{50} of male were significantly different from female in rats of SD and wistar,respectively, and LD-{50} of male is 7.66 times and 6.74 times as large as female in SD and wistar rats, respectively. The LD-{50} of male were not different from female in mice of Kunming and BALB/c, respectively." @default.
- W2356956633 created "2016-06-24" @default.
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- W2356956633 date "2004-01-01" @default.
- W2356956633 modified "2023-09-25" @default.
- W2356956633 title "Acute Toxicity of “Yao-Tong-Ning” Capsule by Oral Administration in Rats and Mice" @default.
- W2356956633 hasPublicationYear "2004" @default.
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