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- W2356972009 abstract "Objective To evaluate relation between heart function and endothelin-1(ET-1) level,nitric oxide(NO)level in the patients suffering from chronic ischemic heart disease.Methods One hundred and twenty one patients with chronic ischemic heart disease and 37 healthy individuals were included in the study.Plasma ET-1 levels of all subjects were measured using ELISA and plasma NO levels were measured using EIA.Left ventricular ejection fraction(LVEF)was measured by echocardiography.Results The ET-1 level of patients was significantly higher than that of controls(P0.05,P0.01).The ET-1 level increased significantly upon the progression from NHYA Class I to IV(P0.01).The NO level of patients was significantly lower than that of controls(P0.01).The NO level decreased significantly upon the progression from NHYA Class I to IV(P0.01).Conclusion In chronic ischemic heart disease,the level of plasma ET-1 is increased and the level of plasma NO is decreased with the severity of cardiac failure." @default.
- W2356972009 created "2016-06-24" @default.
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- W2356972009 date "2007-01-01" @default.
- W2356972009 modified "2023-09-26" @default.
- W2356972009 title "The Relationship between Cardiac Function and Plasma Endothelin-1 and Nitric Oxide in Chronic Ischemic Heart Disease" @default.
- W2356972009 hasPublicationYear "2007" @default.
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