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- W2357014959 abstract "Objective To investigate the prevalence and risk factors of unexplained elevated serum alanine aminotransferase(ALT) activity in Shanghai Pudong new district.Methods A cross-sectional survey with multiple-stage and random sampling was performed,which included questionnaire,anthroposomatological datas,plasma glucose,lipid profile,ALT activity and real-time ultrasonography.Participants with elevated ALT activity further received HBsAg determination and normal ALT subjects were seved as control group.Results A total of 1 942 adult residents of Shanggang community participated in this survey.The prevalence of unexplained elevated ALT activity(without hepatitis B infection and without excessive alcohol intake) was 10.14%.The prevalence of glucose and lipid metabolic disorders in elevated serum ALT activity group was significantly higher than that in the control group.Multiple logistic regression analysis demonstrated that young age,diastolic blood pressure,waist circumference,2 h postprandial plasma glucose,triglyceride,fatty liver and hypertension were risk factors of fatty liver.Conclusions Glucose and lipid metabolic disorders together with its associated nonalcoholic fatty liver disease are the main causes of unexplained elevated ALT activity." @default.
- W2357014959 created "2016-06-24" @default.
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- W2357014959 date "2007-01-01" @default.
- W2357014959 modified "2023-09-28" @default.
- W2357014959 title "Prevalence and risk factors of unexplained elevated serum alanine aminotransferase activity in Shanghai Pudong new district" @default.
- W2357014959 hasPublicationYear "2007" @default.
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