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- W2357066125 abstract "Objective:To apply ROS index in the antioxidation evaluation of hygiene food,and compare its sensitivity with other induces.Methods:12-month KM male mice of SPF were randomly grouped into aging controlled group and low,middle,high soy isoflavones groups(0.00 mg/kg b.w、0.08 mg/kg b.w、0.17 mg/kg b.w、0.50 mg/kg b.w separately).Each group had ten mice.After being given the sample for 42 days,hepatocytes' ROS was measured by FC through staining hepatocytes with DCFH-DA,and MDA content,SOD activity,GSH-Px activity were measured by spectrophotometry.Results:Hitogram analysis of FC showed that hepatocytes' ROS level in each dose group decreased significantly(P0.05),MDA content in the low and high dose group decreased(P0.05),the activity of GSH-Px in the middle and high group increased(P0.05),the activity of SOD in the high group increased(P0.05).But the index in the rest groups has no significant change(P0.05).Conclusion:Soy isoflavones had the effect of antioxidation by decreasing free radical level,hepatocytes' ROS level measured by FC could better appraise the antioxidation system of hygiene food." @default.
- W2357066125 created "2016-06-24" @default.
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- W2357066125 date "2006-01-01" @default.
- W2357066125 modified "2023-09-23" @default.
- W2357066125 title "APPLICATION AND SENSITIVE COMPARISION OF ROS INDEX ON ANTIOXIDATION EVALUATION OF HYGIENE FOOD" @default.
- W2357066125 hasPublicationYear "2006" @default.
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