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- W2357077624 abstract "Objective To explore the relationship between increased polyunsaturated fatty acid(PUFA) consumption and coronary heart disease(CHD).Methods By searching PubMed,CENTRAL(the Cochrane central register of controlled trials),CBM,CNKT,WANFANG and VTP,we collected both domestic and overseas published documents on the relationship between increased PUFA consumption and CHD.Systematic review methods were applied to conduct meta-analysis on the randomized clinical trial(RCTs) study results,the combined risk ratio(RR) and the 95% confidence interval(CI) were calculated as well.Results Seven trials met inclusion criteria and 13 257 participants with 969 CHD events.Average PUFA consumption was 14.4%of energy(range 8.0%-20.7%) in intervention groups versus 5.0%of energy(range 4.0%- 6.4%) in controls.The results indicated that increased PUFA consumption can significantly reduce CHD risk(P = 0.000).The overall pooled risk reduction was 19%(RR = 0.81,95%CI 0.69 - 0.94,Z= 13.5,P =0.000).Conclusions The results provide evidence that consuming PUFA significantly reduces CHD risk." @default.
- W2357077624 created "2016-06-24" @default.
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- W2357077624 date "2011-01-01" @default.
- W2357077624 modified "2023-09-26" @default.
- W2357077624 title "Meta-analysis of the relationship between increased polyunsaturated fatty acid consumption and coronary heart disease" @default.
- W2357077624 hasPublicationYear "2011" @default.
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