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- W2357104080 abstract "Objective To investigate the expression of Stat3 and bcl-2,their clinical significances and their relationship with each other in human lung carcinoma.Methods Immunohistochemical methods were used to detected the expression of Stat3 and bcl-2 in 44 lung cancer specimens,their near tissue and normal tissue.Results The positive rates of Stat3(85%,55%) in adenocarcinoma and squamous cell carcinoma were higher than those in tissure near cancer(40%,20%) and nomal tissue(20%,20%)(P0.05).There was significant difference among different histological types(P0.05),no difference present between the positive rate of Stat3 in cancer with and without lymphoid node metastasis(P0.05).There were significant differences among the positive rates of bcl-2 in small cell lung cancer(100%),tissure near cancer(0%) and nomal tissue(0%)(P0.05),but no difference was present between the positive rate of bcl-2 in cancer with and without lymphoid node metastasis(P0.05),and no different present among different histological types(P0.05).The positive rate of Stat3 in lung carcinoma was higher in male(71.43%)than in femal(0%).No correlations were demonstrated between the positive rate of bcl-2 and age.A positive correlation of the expression of Stat3 with that of bcl-2 was identified.Conclusion Stat3 can be markers of lung carcinoma.Positive correlation is demonstrated between the expression of Stat3 and that of bcl-2." @default.
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- W2357104080 date "2008-01-01" @default.
- W2357104080 modified "2023-09-27" @default.
- W2357104080 title "Expression of Stat3 and bcl-2 in lung cancer and their clinical significance" @default.
- W2357104080 hasPublicationYear "2008" @default.
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