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- W2357107276 abstract "Objective:To observe the effect of Astragalus Heart-Protecting Decoction(AHPD) in prevention and treatment of acute myocardial ischemia(AMI) induced by ligation of coronary artery(LCA).Method:48 rats were randomly divided equally into four groups,group A was treated with Compound Danshen Dripping Pills(CDDP),group B was treated with AHPD,group C and group D were seperately regarded as control group and sham-operated group.2 weeks later,models of rats with AMI were made by LCA.After 3 hours, Left ventricular systolic pressure(LVSP),dp/dtmax and the changes of myocardial histopathology were observed.Results: After treatment,the levels of LVSP,dp/dtmax were significantly higher than that in the control group(P0.05 or P0.01),furthermore,the changes of myocardial histopathology were statistically better than that in the control group,As compared with CDDP group,there was no statistical difference between them(P0.05).Conclusion: AHPD can act against myocardial ischemia effectively by means of enforcing Qi,activating blood and deleting spider,one of the preventive and therapeutic mechanisms of which may be related with enhancing myocardial systolic power and resisting(sustaining) the necrosis and oppotosis of myocardial cells,which shows the splendid future of Traditional Chinese Medicine in preventing and treatment of acute myocardial ischemia." @default.
- W2357107276 created "2016-06-24" @default.
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- W2357107276 date "2008-01-01" @default.
- W2357107276 modified "2023-09-25" @default.
- W2357107276 title "Experimental Study in Heart Function and the changes of myocardial histopathology of Astragalus Heart-Protecting Decoction on Rats with Acute Myocardial Ischemia" @default.
- W2357107276 hasPublicationYear "2008" @default.
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