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- W2357124737 abstract "Objective:To determine the levels of chemokine receptors CXCR1,CXCR4 and IL-8,SDF-1α in codyloma acuminatum(CA) patients.Methods: Real-time quantitative PCR technique was applied to quantitatively analyze CXCR1 and CXCR4 mRNA expression levels in peripheral blood mononuclear cells(PBMC) and lesions,two-colour flow cytometry was used to detect CXCR1 expression cells in blood leucocytes,serum levels of IL-8 and SDF-1α were measured by double antibody sandwich enzyme-linked immunosorbent assay(ELISA) in 30 cases of diagnosed CA patients( 3 months of the course of disease) and 30 healthy controls.Results:The CXCR4 and SDF-1α levels in CA patients were significantly higher than that of the normal controls(P0.01).Conclusion:The increased CXCR4 and SDF-1α may be involved in the pathogenesis of CA." @default.
- W2357124737 created "2016-06-24" @default.
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- W2357124737 date "2011-01-01" @default.
- W2357124737 modified "2023-09-23" @default.
- W2357124737 title "Chemokine receptors CXCR1,CXCR4 and ligands levels in patients with condyloma acuminatum" @default.
- W2357124737 hasPublicationYear "2011" @default.
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