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- W2357165426 abstract "ObjectiveTo investigate the antihypertensive efficacy and safety of Lercanidipine on patients with mild and moderate hypertension.Methods130 patients(age 30-75) with mild to moderate essential hypertension were treated with Lercanidipine for 4 weeks,and blood pressures were recorded.If these were not effective,the once-daily dosage was doubled for addition 4 weeks.Adverse effects,blood pressure,heart rate,haemoglobin,blood platelet,blood bilirubin,creatinine,blood glucose,total cholesterol,HDL cholesterol,LDL cholesterol,triglycerides,Na+ and K+ were detected before treatment and at the end of 4 and 8 weeks after treatment.ResultsPressures decreased from(156.4±11.2)/(98.6±7.6) mm Hg to(142.8±12.4)/(85.4±8.2) mm Hg and(140.6±10.8)/(83.2±9.1) mm Hg after 4 weeks and 8 weeks treatment with Lercanidipine(1 mm Hg=0.133 kPa),it decreased significantly(P0.05).During the study period,six patients(4.61%) had adverse effects,four(3.08%) had mild ankle edema,two(1.54%) had headache and facial flushing,and one had palpitations(0.77%).Haemoglobin,blood platelet,blood bilirubin,creatinine,blood glucose,total cholesterol,HDL cholesterol,LDL cholesterol,triglycerides,Na+ and K+ were stable during study period.ConclusionAntihypertensive efficacy of Lercanidipine was confirmed and it was well tolerability." @default.
- W2357165426 created "2016-06-24" @default.
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- W2357165426 date "2009-01-01" @default.
- W2357165426 modified "2023-09-24" @default.
- W2357165426 title "Clinical Study of Antihypertensive Efficacy and Safety of Lercanidipine" @default.
- W2357165426 hasPublicationYear "2009" @default.
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