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- W2357200809 abstract "Objective To investigate the effect of the water extract from Sonchus L(SOL) on the ultrastructural change of myocardial tissue in Alloxan-induced diabetic mice.Methods Diabetic models were induced by the i.v.injection of Alloxan(140mg/kg) in ICR mice and mice were divided into different groups,which were given SOL(4g/kg,2g/kg,1g/kg),Metformin or normal saline intragastrically once a day for four weeks.Blood glucose and body weight were monitored on the 7th,14th,21st and 28th day.The blood was taken for serum insulin checking.Myocardium was collected for observing the effects of SOL on the ultrastructural change of myocardial tissue.Results After the intervention,comparing with model group,the myocardial hypertrophy and necrosis were improved in SOL groups with decreased interstitial and neatly arranged muscle filament,especially in SOL medium group.Conclusion Water extract from Sonchus L can improve the injury of myocardium ultrastructure in Alloxan-induced diabetic mice,thus delayed occurrence and development of diabetic cardial injury." @default.
- W2357200809 created "2016-06-24" @default.
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- W2357200809 date "2010-01-01" @default.
- W2357200809 modified "2023-09-23" @default.
- W2357200809 title "The effects of Fluvastatin on the Ultrastructural changes of cardiocyte of diabetic rats" @default.
- W2357200809 hasPublicationYear "2010" @default.
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