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- W2357275318 abstract "Objective To investigate the mechanism and conditions of the influences of contrast media on renal vascular tone, and the role in which endothelin and NO may play. Methods The experiment was conducted by measuring the diameter of isolated perfused rat renal artery. The changes in diameter were observed as the arteries were superfused with contrast media, endothelin, NO and other agents. Results Contrast media significantly and selectively enhanced the arterial sensitivity to endothelin. This alteration was mediated by ETA receptor and was not influenced by osmolarity. Contrast media significantly and selectively decreased the arterial sensitivity to NO, which was mainly induced by osmolar charges. Conclusion Contrast media can selectively alter the sensitivity of renal arteries to endothelin and NO." @default.
- W2357275318 created "2016-06-24" @default.
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- W2357275318 date "1999-01-01" @default.
- W2357275318 modified "2023-09-24" @default.
- W2357275318 title "Contrast media alter the potency of endothelin and NO on renal arteries" @default.
- W2357275318 hasPublicationYear "1999" @default.
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