Matches in SemOpenAlex for { <https://semopenalex.org/work/W2357314979> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2357314979 abstract "Objective To observe the anti-inflammatory and analgesic effects of CNZ,an optimized prescrition of Liushen Wan based on our previous studies,so as to provide some pharmacological evidence for its further clinical use. Methods Both acetic-acid-induced increased mouse vascular permeability and carrageenan-induced mouse footpad edema were used to study the anti-inflammatory activity of CNZ.Meanwhile,its analgesic activity was evaluated in mice model of pain induced by thermal stimulus and acetic acid.The above activities were compared with those of Liushen Wan.Results CNZ significantly reduced acetic-acid-induced dye leakage at the doses of 16,32 and 64mg/kg after single oral administration.Meanwhile,CNZ at the two higher doses also markedly inhibited carrageenan-induced foot- pad edema,which exerted the strongest effect at 3 hours after carrageenan injection,and lasted over 5 hours.On the other hand,CNZ remarkably suppressed acetic-acid-induced writhing response at low,moderate-and high-doses, and significantly prolonged pain threshold in hot plate assay at moderate-and high-doses 0.5 hour after oral adminis- tration,lasting over 3 hours.Overall,its potency was similar to that of Liushen Wan.Conclusion CNZ has significant anti-inflammatory and analgesic activities." @default.
- W2357314979 created "2016-06-24" @default.
- W2357314979 creator A5020248771 @default.
- W2357314979 date "2008-01-01" @default.
- W2357314979 modified "2023-09-23" @default.
- W2357314979 title "Preliminary Studies on Anti-Inflammatory and Analgesic Activities of Optimized Liushen Wan(CNZ)" @default.
- W2357314979 hasPublicationYear "2008" @default.
- W2357314979 type Work @default.
- W2357314979 sameAs 2357314979 @default.
- W2357314979 citedByCount "0" @default.
- W2357314979 crossrefType "journal-article" @default.
- W2357314979 hasAuthorship W2357314979A5020248771 @default.
- W2357314979 hasConcept C126322002 @default.
- W2357314979 hasConcept C185592680 @default.
- W2357314979 hasConcept C202751555 @default.
- W2357314979 hasConcept C2776673659 @default.
- W2357314979 hasConcept C2780820201 @default.
- W2357314979 hasConcept C2780886150 @default.
- W2357314979 hasConcept C2781227287 @default.
- W2357314979 hasConcept C3673659 @default.
- W2357314979 hasConcept C42219234 @default.
- W2357314979 hasConcept C55493867 @default.
- W2357314979 hasConcept C57992300 @default.
- W2357314979 hasConcept C71924100 @default.
- W2357314979 hasConcept C98274493 @default.
- W2357314979 hasConceptScore W2357314979C126322002 @default.
- W2357314979 hasConceptScore W2357314979C185592680 @default.
- W2357314979 hasConceptScore W2357314979C202751555 @default.
- W2357314979 hasConceptScore W2357314979C2776673659 @default.
- W2357314979 hasConceptScore W2357314979C2780820201 @default.
- W2357314979 hasConceptScore W2357314979C2780886150 @default.
- W2357314979 hasConceptScore W2357314979C2781227287 @default.
- W2357314979 hasConceptScore W2357314979C3673659 @default.
- W2357314979 hasConceptScore W2357314979C42219234 @default.
- W2357314979 hasConceptScore W2357314979C55493867 @default.
- W2357314979 hasConceptScore W2357314979C57992300 @default.
- W2357314979 hasConceptScore W2357314979C71924100 @default.
- W2357314979 hasConceptScore W2357314979C98274493 @default.
- W2357314979 hasLocation W23573149791 @default.
- W2357314979 hasOpenAccess W2357314979 @default.
- W2357314979 hasPrimaryLocation W23573149791 @default.
- W2357314979 hasRelatedWork W173838730 @default.
- W2357314979 hasRelatedWork W1998788342 @default.
- W2357314979 hasRelatedWork W2044653637 @default.
- W2357314979 hasRelatedWork W2123843261 @default.
- W2357314979 hasRelatedWork W2184899139 @default.
- W2357314979 hasRelatedWork W2278897785 @default.
- W2357314979 hasRelatedWork W2292383171 @default.
- W2357314979 hasRelatedWork W2312591112 @default.
- W2357314979 hasRelatedWork W2367599041 @default.
- W2357314979 hasRelatedWork W2370590007 @default.
- W2357314979 hasRelatedWork W2381157883 @default.
- W2357314979 hasRelatedWork W2394025969 @default.
- W2357314979 hasRelatedWork W2409512165 @default.
- W2357314979 hasRelatedWork W2567640190 @default.
- W2357314979 hasRelatedWork W2567706114 @default.
- W2357314979 hasRelatedWork W3007432541 @default.
- W2357314979 hasRelatedWork W2181473260 @default.
- W2357314979 hasRelatedWork W2182029287 @default.
- W2357314979 hasRelatedWork W2338159468 @default.
- W2357314979 hasRelatedWork W3084808012 @default.
- W2357314979 isParatext "false" @default.
- W2357314979 isRetracted "false" @default.
- W2357314979 magId "2357314979" @default.
- W2357314979 workType "article" @default.