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- W2357321595 abstract "Objective Research of the relationship between the level change of plasma vascular endothelial growth factor, C-reactive protein and arteriosclerosis in patients with type 2 diabetes and discuss the possible mechanism of action. Methods Enzyme-linked immunosorbent assay(ELISA)and the immune turbidimetry were used respectively to test the levels of plasma VEGF and CRP in patients with type 2 diabetes(total 63 cases, 33 simple diabetes mellitus and 30 accompanied by arteriosclerosis)and healthy objects(total 31 cases). Analyse the relationship between levels change and arteriosclerosis. Results The levels of plasma VEGF and CRP in patients with type 2 diabetes accompanied by arteriosclerosis group was higher than that of simple diabetes mellitus group and normal group. Logistic regression analysis show that SBP, TC, TG, HDL, HbA 1 c, VEGF, CRP are correlated to arteriosclerosis. Multivariate correlation analysis show VEGF is correlate to WHR, SBP, FPG, TC, TG, HDL, HbA 1 c and CRP(P0.05);CRP is correlate to WHR, SBP, FPG, TC, TG, HDL, HbA1c, VEGF(P0.05). Conclusions VEGF and CRP are risk factors for atherosclerosis occurs.They may be jointly participate in the formation process of atherosclerosis. Control of blood pressure, blood fat, blood sugar, reduce weight, anti-inflammatory and other comprehensive treatment is beneficial to delay the occurrence and development of atherosclerosis." @default.
- W2357321595 created "2016-06-24" @default.
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- W2357321595 date "2013-01-01" @default.
- W2357321595 modified "2023-09-23" @default.
- W2357321595 title "Relationship Between Vascular Endothelial Growth Factor, C-reactive Protein and Arteriosclerosis In Patients With Type 2 Diabetes" @default.
- W2357321595 hasPublicationYear "2013" @default.
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