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- W2357352328 abstract "Objective:To study the expression of c-FLIP in osteosarcoma,and investigate its clinical significance and prognostic value.Methods: Total of 47 cases of osteosarcoma,25 of osteochondroma,and 8 of normal bone tissue which have complete clinical information were collected.The expression of c-FLIP was detected with Immunohistochemistry method(SP) and Western-blot technique to analyze the relation between c-FLIP and tumor histological characteristics and prognosis.Results: The positive expression rate of c-FLIP in 47 patients with osteosarcoma was 83%(39/ 47),which was significantly higher than that in the patients with osteochondroma(16%,P0.01).A negative correlation was found between the expression of c-FLIP and sex,age,time,tumor size,pathology types,as well as the metastasis of osteosarcoma(P0.05),but there was a positive correlation with clinical Ennecking stages(P0.05).Conclusion: Over expression of c-FLIP may be correlated with the carcinogenesis and progress of osteosarcoma." @default.
- W2357352328 created "2016-06-24" @default.
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- W2357352328 date "2011-01-01" @default.
- W2357352328 modified "2023-09-28" @default.
- W2357352328 title "The expression and clinical significance of c-FLIP in osteosarcoma" @default.
- W2357352328 hasPublicationYear "2011" @default.
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