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- W2357402571 abstract "[Objective]To investigated the effect of intraspinal grafting of Adenovirus-mediated BDNF ex vivo transgene myoblasts cells and methylprednisolone on N-methyl-D-aspartate(NMDA) receptors after spinal cord injury(SCI) in rats.[Method]Experimental rats were divided into four groups:the Contusion injury group(group A), Contusion plus transplants of ex vivo transgene myoblasts cells to injured site group(group B),Contusion plus methylprednisolone group(group C) and Contusion plus transplants of ex vivo transgene myoblasts cells plus methylprednisolone group(group D).After operation 1,3,7,14 days,antibodies to the radioligand assay of [3H]MK-801 was used to assess NMDA receptors in the spinal cord.[Result]The radioligand assay of [3H]MK-801 was reduced in all groups in injured cord segments,they are ABCD(P0.05).[Conclusion]It indicates that the methyprednisolone, and BDNF transgene myoblasts cells must be mediated by a mechanism that withstands enhance of NMDA receptor function andcan attenuate secondary SCI." @default.
- W2357402571 created "2016-06-24" @default.
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- W2357402571 date "2005-01-01" @default.
- W2357402571 modified "2023-09-28" @default.
- W2357402571 title "Effect of intraspinal grafting of adenovirus-mediated BDNF ex vivo transgene myoblasts cells and methylprednisolone on N-methyl-D-aspartate(NMDA) receptors after cervical spinal cord contusion in rats" @default.
- W2357402571 hasPublicationYear "2005" @default.
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