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- W2357432783 abstract "OBJECTIVE: To evaluate the necessity,accuracy and clinical value of sentinel lymph node(SLN) biopsy in patients with early stage cervical cancer.METHODS: Totally 80 patients with early stage cervical cancer underwent hysterectomy and pelvic lymph nodes dissection.SLN detection was received with preoperative an intracervical injection of 99Tcm-sulfur colloid and blue dye.All resected nodes were submitted to the pathological examination and immunohistochemistry.RESULTS: A total of 227 SLNs were identified in 76 patients were detected.Sensitivity and specificity of the SLN biopsy were 78.9% and 97.4%,the false-negative rate was 10.5%.Totally 77%(174) SLN were found in the internal iliac and obturator lymph nodes,18%(40) in the external iliac lymph nodes,4%(10) were in the common iliac lymph nodes,1%(3)in the parametrical lymph nodes.The detection rate of SLN with combined radioisotope and the blue dye was 96.0%,radioisotope alone was 90.0% and blue dye was 80.0%(P=0.03).The detection rate of SLN with blue dye was 93.3% in the followed 30 patient.The 408 resected nodes(SLN and non-SLN) were CK19 negative with immunohistochemistry.CONCLUSIONS: Detection of SLN in patients with early stage cervical cancer is simple and feasible.Criterion of detection should be clear.The representation of regional SLN pathology requires further evaluation.The clinical significance and method of SLN technology and micrometastasis in early cervical cancer need to be further researched." @default.
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- W2357432783 date "2011-01-01" @default.
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- W2357432783 title "Sentinel lymph node detection in patients with early stage cervical cancer" @default.
- W2357432783 hasPublicationYear "2011" @default.
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