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- W2357446473 abstract "Objective To assess the mast cells expression of the liver in patients with biliary atresia, and to analyze the relationships between the mast cells expression, liver damage, and the prognosis in pediatric patients with biliary atresia. Methods The mast cells expression of the liver in patients with biliary atresia were assayed by toluidine blue and immunohistochemical stain (chymase). Based on patients' liver function, 30 pediatric patients with biliary atresia were divided into two groups (good and poor outcome groups). Five liver samples autopsy infants who were died of non digestive tract diseases were served as control. Results The degree of mast cells expression was higher in patients with biliary atresia than that in controls, higher in poor outcome group than that in good outcome group, higher in severe fibrosis group than that of in mild fibrosis group. Conclusions Mast cells may play an important role in progressive liver damage and fibrosis in patients with biliary atresia. The over expression of mast cell in the liver of patients with biliary atresia indicates more severe degree of liver fibrosis and poorer prognosis of patients with biliary atresia." @default.
- W2357446473 created "2016-06-24" @default.
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- W2357446473 date "2010-01-01" @default.
- W2357446473 modified "2023-10-17" @default.
- W2357446473 title "Expression of mast cell correlated with clinical outcomes in children with biliary atresia" @default.
- W2357446473 hasPublicationYear "2010" @default.
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