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- W2357479457 abstract "Objective To observe the effect of Danshen Chuanxiongqin injection combined with pancreatic kininogenase on the treatment of early diabetic nephropathy( DN) patients. Methods 76 cases of early diabetic nephropathy patients were randomly divided into treatment group and control group. Patients in two groups were treated with pancreatic kallikrein 40 U,intramuscular injection,once a day. Patients in the treatment group were added with Danshen Chuanxiongqin injection 10 mL plus normal saline 250 mL,1 times / day,intravenous infusion,2 weeks. The changes of serum creatinine( Cr),blood urea nitrogen( BUN),glomerular filtration rate( GFR),blood lipid( TC,TG) and 24 h urinary protein before and after treatment were measured. Results In the control group,Cr,TC,TG and 24 h urine total protein after treatment were decreased significantly as compared with those before treatment( P 0. 05). There was no significant changes between before and after treatment on BUN and GFR in control group( P 0. 05). The treatment group Cr,TC,TG,24 h urine total protein,BUN and GFR after treatment were decreased significantly as compared with those before treatment in treatment group( P 0. 01). Compared with the control group,the difference was statistically significant( P 0. 05). Conclusion Danshen Chuanxiongqin injection combined with pancreatic kininogenase for treatment of early diabetic nephropathy can significantly decrease the Cr,BUN,24 h urine protein content and lipid levels,increase GFR and improve renal function." @default.
- W2357479457 created "2016-06-24" @default.
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- W2357479457 date "2014-01-01" @default.
- W2357479457 modified "2023-09-23" @default.
- W2357479457 title "Observation of therapeutic effect of Danshen Chuanxiongqin injection combined with pancreatic kininogenase on early diabetic nephropathy patients" @default.
- W2357479457 hasPublicationYear "2014" @default.
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