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- W2357479568 abstract "The AD8 was developed as a brief instrument to help discriminate signs between normal aging and dementia. This study was aimed to establish the sensitivity and specificity of the AD8 as a screening tool in the nationwide sampling population in Taiwan. From a computerized random sampling, we enrolled 10,432 elderly participants aged 65 years and more. We performed direct questioning with AD8 for the participant or informant interview if the interviewee could not answer properly. We compared their AD8 score with the diagnosis for all-cause dementia which was based on the core clinical criteria recommended by the National Institute on Aging-Alzheimer's Association and the Taiwanese Mental State Examination (TMSE). Sensitivity, specificity, concurrent validity and internal consistency of the AD8 were assessed. Receiver operator characteristic curves (ROC) with calculating Youden index were used to determine the optimal cut-off score. Using the AD8 scored ≥2 as a screening in our population showed biggest area under the ROC (AUC) 0.94 (95% CI 0.93 to 0.96) with sensitivity 0.88% and specificity 0.94%. The Cronbach alpha of the AD8 was 0.87 (95%CI 0.87 to 0.88), suggesting excellent internal consistency. In view of each item of the AD8, the question “forget correct month or year” showed highest predictive value with accuracy rate 0.95 (sensitivity 0.80, specificity 0.97). The Chinese version of AD8 in Taiwan is a good screening tool with high sensitivity and specificity, using score ≥2 to detect demented individuals." @default.
- W2357479568 created "2016-06-24" @default.
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- W2357479568 date "2015-07-01" @default.
- W2357479568 modified "2023-09-27" @default.
- W2357479568 title "P4-142: The sensitivity and specificity of the chinese version of ad8 in a nationwide screening for dementia in taiwan" @default.
- W2357479568 doi "https://doi.org/10.1016/j.jalz.2015.06.1848" @default.
- W2357479568 hasPublicationYear "2015" @default.
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