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- W2357502302 abstract "AIM: To observe the effects of HSYA injection on platelet aggregation and ultra structure in rabbits.METHODS: In vivo experiments,when platelet activating factor(PAF) induced respectively,we observed the impacts of HSYA injection(10 mg/kg,5 mg/kg and 2.5 mg/kg) on platelet aggregation,ultra structural changes of platelets and PAF-induced content of GMP-140.RESULTS:HSYA injection inhibited AA and PAF-induced platelet aggregation(P0.05,P0.01).Scanning electron microscope showed: HSYA injection could reduce the number of aggregation type plateles which were induced by AA and PAF;and make fewer and shorter processes of dendritic platelets(P0.05,P0.01).HSYA injection can reduce the content of GMP-140 in PRP(P0.01).CONCLUSION: HSYA injection can antagonism PAF-induced platelet aggregation,inhibit the activation of platelets and reduce the content of GMP-140.Thus for,there will be more choices for clinical using of anti-platelet aggregation drugs." @default.
- W2357502302 created "2016-06-24" @default.
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- W2357502302 date "2012-01-01" @default.
- W2357502302 modified "2023-09-22" @default.
- W2357502302 title "Effects of HSYA injection on platelet aggregation,ultrastructure and the content of PAF induced GMP-140 in PRP in rabbits" @default.
- W2357502302 hasPublicationYear "2012" @default.
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