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- W2357510639 abstract "Objective To explore the effects of low energy intravenous He-Ne laser irradiation of blood (ILIB) on cell proliferation, apoptosis and genotoxicity of lymphocytes in patients with cerebral infarction (CI). Methods The lymphocytes in peripheral blood in patients with CI were sampled before and after treatment and cultured, and then, some parameters such as the mitosis index (MI), cell cyclical kinetics index (CCKI), sister chromatid exchanges frequencies (SCEF) and apoptosis were analyzed in order to explore the effects of ILIB on lymphocytes. Results The proliferative activities of lymphocytes were significantly increased by ILIB (P0.05) as compared with that before the treatment and that of the control group. There was a correlation between the proliferation and dose of ILIB(P0.001). However, the effects of ILIB on cell cycles of lymphocytes were not significant. There was no significant difference between the treatment group and the control group with regard to CCKI and SCEF no matter before or after treatment (P0.05). After ILIB, the rate of apoptosis in patients with CI was significantly increased when compared with that before treatment and that of the control group, as revealed by flow cytometry (FCM) (P0.001). Conclusion ILIB could increase the proliferative activities leading to higher apoptosis rate of lymphocytes, but have no genotoxicity." @default.
- W2357510639 created "2016-06-24" @default.
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- W2357510639 date "2004-01-01" @default.
- W2357510639 modified "2023-09-23" @default.
- W2357510639 title "Effects of low energy intravenous He-Ne laser irradiation of blood on lymphocytes in patients with cerebral infarction" @default.
- W2357510639 hasPublicationYear "2004" @default.
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