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- W2357547063 abstract "Due to some serious disadvantages such as high cost,low yield and some side effects of antivenom,looking for more ideal antidotes to treat snakebite victims has been becoming important.Naturally,immunoglobulin of egg yolk(IgY)has been given much attentions and become an important object for our developing new antidotes against the snakebites because of IgY's special features in production and effect of neutralization.Current studies show that IgY and mammalian IgG share a similar biological function but they have some striking differences in the structures.IgY is particularly stable at high pressure and across a diverse range of pHs but it is susceptible to high temperature and proteolytic.Compared with IgG,IgY can be produced relatively cheaply and noninvasively and the utility of IgY in immunological assay can reduce the cause of false positive results.The resulting immune response of immunized of hens can be influenced by four main factors:the antigen(dose,molecular weight),the type of adjuvant,the route for antigen injection and interval between immunisations.The purification method can influence the purity and activity of IgY.The development of anti-snake venom IgY and its good neutralizing effects on various toxicological effects caused by snake venoms have been showed in much studies.With the advance in biotechnology,anti-snake venom IgY is expected to be developed into antidote,rapid diagnosis test paper,affinity ligand,oral preparation and so on,the application prospect of anti-snake venom IgY in the research field of snakebite is wide." @default.
- W2357547063 created "2016-06-24" @default.
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- W2357547063 date "2015-01-01" @default.
- W2357547063 modified "2023-09-25" @default.
- W2357547063 title "Immunoglobulin of Egg Yolk(IgY)and Its Research Progress on Treatment of Snakebite" @default.
- W2357547063 hasPublicationYear "2015" @default.
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