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- W2357549278 abstract "Objective:To observe the impact of Staphylococcus aureus accessory gene regulator(agrC)binding peptide on the formation of the biofilm (BF) of Staphylococcus aureus.Methods:The agrC-binding small peptides were prepared artificially,and its impact on biofilm was observed through micro-plate semi-quantitative test and a laser scanning confocal microscope(LSCM).RT-PCR and Western blot were used to observe its impact on the transcription and expression of Autolysin E (altE) and icaA protein.Results:The agrC-binding small peptides could significantly inhibit the BF formation of Staphylococcus aureus in its adhesion aggregation phase and,at the same time,affect the transcription and expression of the factors related to the formation of biofilm.Conclusion:AgrC binding peptides can be used to prevent and treat the early-stage infections caused by the BF of Staphylococcus aureus." @default.
- W2357549278 created "2016-06-24" @default.
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- W2357549278 date "2010-01-01" @default.
- W2357549278 modified "2023-09-25" @default.
- W2357549278 title "The inhibition of Staphylococcus aureus agrC binding peptides on biofilm" @default.
- W2357549278 hasPublicationYear "2010" @default.
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