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- W2357550426 abstract "Objective:To observe the relationship of Yin deficiency and hepatic pathology and genotyping of HLA-DRB1 HLA DQA1 alleles in chronic asymptomatic HBV carrier,and discuss the effect of constitution factor on degrees of inflammatory activity and fibrosis.To improve inflammatory activity and fibrosis by adjusting pathological.Method:According to the diagnostic criteria,105 cases of chronic HBV carriers were selected,then divided into two groups:Yin deficiency(47 cases)and non-Yin deficiency(58 cases).The general condition such as age,gender and family history were recorded.The bioptic liver specimens from 105 cases of patients with chronic asymptomatic HBV carrier were analyzed.The examine of pathogeny,hepatic function and genotyping of HLA-DRB1 HLA DQA1 alleles were tested.Results:Through statistical analysis,there was no significant difference of pathogen indicators(HBsAg,HBV-DNA,HBeAg)and liver functional indices(TBiL,DBiL,ALT,AST,AlB,GLB)between the two groups(P0.05).The difference was not statistically significant on inflammatory activity between the two groups(P0.05).The incidence of fibrosis in patients of Yin deficiency was significantly higher than that in non-Yin deficiency group(P0.05).There was no statistical significance on HLA-DRB1,HLA-DQA1 allele frequency among the degrees of liver pathologic histology in chronic asymptomatic HBV carrier(P0.05).Conclusion:Most chronic asymptomatic HBV carriers had mild liver pathologic histology,but some were moderate and severe hepatitis.The incidence of fibrosis in patients of Yin deficiency was significantly higher than that in non-Yin deficiency group.Yin deficiency has susceptibility to liver fiberosis,further progress to be liver cirrhosis namely." @default.
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- W2357550426 date "2012-01-01" @default.
- W2357550426 modified "2023-09-25" @default.
- W2357550426 title "Study on the Connection of Yin Deficiency and Hepatic Pathology in Chronic Asymptomatic HBV Carrier" @default.
- W2357550426 hasPublicationYear "2012" @default.
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