Matches in SemOpenAlex for { <https://semopenalex.org/work/W2357597818> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2357597818 endingPage "7" @default.
- W2357597818 startingPage "345" @default.
- W2357597818 abstract "To explore the effect of somatostatin on serum interleukin (IL)-6 and tumor necrosis factor (TNF)-alpha in lipopolysaccharide (LPS)-induced septic shock.24 male Wistar rats were randomly divided into 2 groups: intervention group (injected with LPS of Escherichia coli via femoral vein to induce septic shock) and control group (injected with LPS of Escherichia coli and then injected with somatostatin). The mean arterial pressure (MAP), heart rate, respiration rater, and mortality rate were observed before the injection of LPS, and 30, 90, and 360 min after the injection, and the serum IL-6 and TNF-alpha level were detected before the injection of LPS, 30, 90, and 360 min after the injection, or after the death.The IL-6 levels 30 min, 90 min, and 360 min after the injection of the somatostatin intervention group were 233 +/- 47, 212 +/- 33, and 217 +/- 26 mg/L respectively, all significantly lower then those of the control group (308 +/- 56, 260 +/- 32, and 230 +/- 92 mg/L, all P < 0.05). The TNF-alpha level 30 min, 90 min, and 360 min after the injection of the somatostatin intervention group were 450 +/- 82, 417 +/- 92, and 440 +/- 49 mg/L, all significantly lower than those of the control group (607 +/- 149, 517 +/- 74, and 474 +/- 219 mg/L, all P < 0.05). In addition, compared with the control group, the MAP of the somatostatin intervention group increased after 90 min. Two rats in the control group died 30 to 90 min later and 4 rats died 90 to 360 min later, however, 360 min later all rats in the somatostatin intervention group were alive (P = 0.0054).Somatostatin can inhibit the level of serum IL-6 and TNF-alpha in septic shock induced by LPS and improve the survival rate." @default.
- W2357597818 created "2016-06-24" @default.
- W2357597818 creator A5010492600 @default.
- W2357597818 creator A5044624353 @default.
- W2357597818 creator A5048826252 @default.
- W2357597818 creator A5054531184 @default.
- W2357597818 creator A5076881280 @default.
- W2357597818 creator A5086880570 @default.
- W2357597818 date "2007-01-30" @default.
- W2357597818 modified "2023-09-29" @default.
- W2357597818 title "[The effects of somatostatin on serum interleukin-6 and tumor necrosis factor-alpha in lipopolysaccharide-induced septic shock: experiment with rats]." @default.
- W2357597818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17456366" @default.
- W2357597818 hasPublicationYear "2007" @default.
- W2357597818 type Work @default.
- W2357597818 sameAs 2357597818 @default.
- W2357597818 citedByCount "3" @default.
- W2357597818 countsByYear W23575978182014 @default.
- W2357597818 countsByYear W23575978182022 @default.
- W2357597818 countsByYear W23575978182023 @default.
- W2357597818 crossrefType "journal-article" @default.
- W2357597818 hasAuthorship W2357597818A5010492600 @default.
- W2357597818 hasAuthorship W2357597818A5044624353 @default.
- W2357597818 hasAuthorship W2357597818A5048826252 @default.
- W2357597818 hasAuthorship W2357597818A5054531184 @default.
- W2357597818 hasAuthorship W2357597818A5076881280 @default.
- W2357597818 hasAuthorship W2357597818A5086880570 @default.
- W2357597818 hasConcept C126322002 @default.
- W2357597818 hasConcept C134018914 @default.
- W2357597818 hasConcept C141071460 @default.
- W2357597818 hasConcept C17991360 @default.
- W2357597818 hasConcept C2775944032 @default.
- W2357597818 hasConcept C2776297358 @default.
- W2357597818 hasConcept C2776452961 @default.
- W2357597818 hasConcept C2777628635 @default.
- W2357597818 hasConcept C2777953023 @default.
- W2357597818 hasConcept C2778384902 @default.
- W2357597818 hasConcept C2778690821 @default.
- W2357597818 hasConcept C2778754761 @default.
- W2357597818 hasConcept C2781300812 @default.
- W2357597818 hasConcept C2910236225 @default.
- W2357597818 hasConcept C49453240 @default.
- W2357597818 hasConcept C503630168 @default.
- W2357597818 hasConcept C64943373 @default.
- W2357597818 hasConcept C71924100 @default.
- W2357597818 hasConcept C74172505 @default.
- W2357597818 hasConcept C84393581 @default.
- W2357597818 hasConceptScore W2357597818C126322002 @default.
- W2357597818 hasConceptScore W2357597818C134018914 @default.
- W2357597818 hasConceptScore W2357597818C141071460 @default.
- W2357597818 hasConceptScore W2357597818C17991360 @default.
- W2357597818 hasConceptScore W2357597818C2775944032 @default.
- W2357597818 hasConceptScore W2357597818C2776297358 @default.
- W2357597818 hasConceptScore W2357597818C2776452961 @default.
- W2357597818 hasConceptScore W2357597818C2777628635 @default.
- W2357597818 hasConceptScore W2357597818C2777953023 @default.
- W2357597818 hasConceptScore W2357597818C2778384902 @default.
- W2357597818 hasConceptScore W2357597818C2778690821 @default.
- W2357597818 hasConceptScore W2357597818C2778754761 @default.
- W2357597818 hasConceptScore W2357597818C2781300812 @default.
- W2357597818 hasConceptScore W2357597818C2910236225 @default.
- W2357597818 hasConceptScore W2357597818C49453240 @default.
- W2357597818 hasConceptScore W2357597818C503630168 @default.
- W2357597818 hasConceptScore W2357597818C64943373 @default.
- W2357597818 hasConceptScore W2357597818C71924100 @default.
- W2357597818 hasConceptScore W2357597818C74172505 @default.
- W2357597818 hasConceptScore W2357597818C84393581 @default.
- W2357597818 hasIssue "5" @default.
- W2357597818 hasLocation W23575978181 @default.
- W2357597818 hasOpenAccess W2357597818 @default.
- W2357597818 hasPrimaryLocation W23575978181 @default.
- W2357597818 hasRelatedWork W2013820236 @default.
- W2357597818 hasRelatedWork W2021396499 @default.
- W2357597818 hasRelatedWork W2118174479 @default.
- W2357597818 hasRelatedWork W2352128661 @default.
- W2357597818 hasRelatedWork W2357597818 @default.
- W2357597818 hasRelatedWork W2362167551 @default.
- W2357597818 hasRelatedWork W2391544553 @default.
- W2357597818 hasRelatedWork W2417055631 @default.
- W2357597818 hasRelatedWork W3143110916 @default.
- W2357597818 hasRelatedWork W1929770229 @default.
- W2357597818 hasVolume "87" @default.
- W2357597818 isParatext "false" @default.
- W2357597818 isRetracted "false" @default.
- W2357597818 magId "2357597818" @default.
- W2357597818 workType "article" @default.