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- W2357641838 abstract "Objective To observe cellular immune function and side effect of ginsenoside Rg3 combined with gemcitabine plus cisplatin(GP) regimen for non-small-cell lung cancer(NSCLC).Methods Forty patients with stageⅡ-Ⅲa NSCLC of aged person were randomly divided into GP adding ginsenoside Rg3 group(observation group) and GP group(control group),twenty in each group.After two cycles,the cellular immune function,the level of vascular endothelial growth factor(VEGF) and the side reaction were evaluated.Results The improvement of CD4/CD8 ratio and natural killer cell positive ratio in observation group was higher than that before treatment and it was higher than that in control group(P0.05).The levels of VEGF in two groups were decreased as compared with that before treatment(P0.05).After treatment,the VEGF levels and incidence of toxicity leucopenia in observation group were lower than those in control group(P0.05).Karnofslcy scale was improved in observation group(P0.05).Conclusion Ginsenoside Rg3 combined GP regimen was safe in treatment of elderly NSCLC.Ginsenoside Rg3 capsules can decrease the occurring of leucopenia and improve cellular immune function and the patient's quality of life." @default.
- W2357641838 created "2016-06-24" @default.
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- W2357641838 date "2011-01-01" @default.
- W2357641838 modified "2023-09-26" @default.
- W2357641838 title "Observation of ginsenoside Rg3 combined with chemotherapy as adjuvant treatment for elder non-small-cell lung cancer patients" @default.
- W2357641838 hasPublicationYear "2011" @default.
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